Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | GLS | O94925 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722754 | 0.79 | TRPV1 (0.34) | TRPV1GLSCHRNB2CHRNA4 | |
| SCHEMBL29544097 | 0.68 | HRH4 (0.47) | GLSHRH4MEN1KMT2A | |
| SCHEMBL18890299 | 0.68 | HRH4 (0.47) | GLSHRH4MEN1KMT2A | |
| SCHEMBL18790702 | 0.68 | CYP11B2 (0.52) | — | |
| SCHEMBL7678390 | 0.66 | SORD (0.48) | — | |
| SCHEMBL18890300 | 0.64 | GLS (0.52) | TRPV1GLS | |
| SCHEMBL8717874 | 0.63 | HTR3E (0.53) | MEN1KMT2A | |
| SCHEMBL5525542 | 0.62 | ALDH1A1 (0.56) | KMT2A | |
| SCHEMBL29046568 | 0.62 | SIRT2 (0.38) | — | |
| SCHEMBL209742 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | disclosed |