Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18794813 | 0.90 | METAP2 (0.41) | METAP2GRIN1GRIN2APGR | |
| SCHEMBL18794837 | 0.83 | SLC6A9 (0.38) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL18794830 | 0.82 | GRIN1 (0.33) | METAP2GRIN1GRIN2AGRIN2B | |
| SCHEMBL18794819 | 0.78 | GRIN1 (0.51) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL18794865 | 0.76 | SLC6A3 (0.46) | GRIN1GRIN2A | |
| SCHEMBL18822477 | 0.75 | DRD2 (0.38) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL18794831 | 0.75 | DRD2 (0.38) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL18822478 | 0.75 | DRD2 (0.38) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL18794816 | 0.75 | SLC6A4 (0.42) | — | |
| SCHEMBL28546096 | 0.70 | GRIN1 (0.43) | GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070793-A1 | NOVEL FLUORINATED HETEROCYCLE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2017-05-04 | — | — | WO | claimed |
| WO-2017070793-A1 | NOVEL FLUORINATED HETEROCYCLE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017070793-A1 | NOVEL FLUORINATED HETEROCYCLE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2017-05-04 | — | — | WO | disclosed |