SCHEMBL18796201

SCHEMBL18796201

CC(C)(C)C(=O)C1CCCCC1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.49
MAPK1 P28482 1/20 0.46
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
KMT2A Q03164 1/20 0.42
HTT P42858 1/20 0.36
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.33
CCR2 P41597 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP1A2 P05177 1/20 0.33
RECQL P46063 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HBB P68871 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14436613 0.94 MCL1 (0.42) MCL1MAPK1CA1CA2CA4
SCHEMBL3107746 0.82 MCL1 (0.50) MCL1MAPK1CA1CA2CA4
SCHEMBL16935259 0.80 MCL1 (0.49) MCL1MAPK1CA1CA2CA4
SCHEMBL4751506 0.78 MCL1 (0.46) MCL1MAPK1CA1CA2CA4
SCHEMBL14484973 0.77 MCL1 (0.46) MCL1MAPK1CA1CA2CA4
SCHEMBL63339 0.77 MCL1 (0.53) MCL1MAPK1CA1CA2CA4
SCHEMBL6283782 0.76 MAPK1 (0.46) MCL1MAPK1CA1CA2CA4
SCHEMBL18167166 0.75 MCL1 (0.41) MCL1MAPK1CA1CA2CA4
SCHEMBL15364870 0.75 MCL1 (0.52) MCL1MAPK1CA1CA2CA4
SCHEMBL11114524 0.75 MCL1 (0.52) MCL1MAPK1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-21 US disclosed
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-03-03 US disclosed
US-12543738-B2 3-(pyridazin-4-yl)-5,6-dihydro-4H-1,2,4-oxadiazine derivatives as fungicides for crop protection BAYER AKTIENGESELLSCHAFT (DE) 2026-02-10 US disclosed
EP-4149929-B1 TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AG (DE) 2026-01-28 EP disclosed
US-12534456-B2 Heterocyclyl pyridines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-01-27 US disclosed
US-12501900-B2 Heterocyclyl pyridazine as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-12414565-B2 Pyridazine (THIO)amides as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2025-09-16 US disclosed
EP-3887362-B1 PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AG (DE) 2025-06-18 EP disclosed
WO-2025078128-A1 PYRIDAZIN-3-ONE-4-YLOXADIAZINES AS NOVEL FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-04-17 WO disclosed
WO-2025032038-A1 PYRIDAZIN-4-YLOXADIAZINES AS NOVEL FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-02-13 WO disclosed
US-20190335753-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-11-07 US disclosed
US-20190233444-A1 TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-08-01 US disclosed
EP-3478659-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2019-05-08 EP disclosed
CN-109476606-A Benzosultams and analogs and their use as fungicides 拜耳作物科学股份公司 2019-03-15 CN disclosed
WO-2018202706-A1 TRISUBSTITUTEDSILYLHETEROARYLOXYQUINOLINES AND ANALOGUES BAYER AKTIENGESELLSCHAFT (DE) 2018-11-08 WO disclosed
WO-2018202712-A1 TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES BAYER AKTIENGESELLSCHAFT (DE) 2018-11-08 WO disclosed
EP-3368514-A1 TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES Bayer CropScience Aktiengesellschaft (DE) 2018-09-05 EP disclosed
CN-108349897-A Trisubstituted silylphenoxyheterocycles and analogs 拜耳作物科学股份公司 2018-07-31 CN disclosed
WO-2018007323-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-11 WO disclosed
WO-2017072283-A1 TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12414565-B2 Pyridazine (THIO)amides as fungicidal compounds PNPO, TPMT, BLVRB MCL1 4346/4885MAPK1 3000/4885CA1 4477/4885
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides CBR1, CBR3, NOX1 MCL1 1049/4885MAPK1 1356/4885CA1 1244/4885
US-12543738-B2 3-(pyridazin-4-yl)-5,6-dihydro-4H-1,2,4-oxadiazine derivatives as fungicides for crop protection CYP4Z1, HPD, CYP4B1 MCL1 2747/4885MAPK1 2100/4885CA1 3617/4885
US-12501900-B2 Heterocyclyl pyridazine as fungicidal compounds PNPO, PDXK, BLVRB MCL1 3783/4885MAPK1 2171/4885CA1 4759/4885
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS CBR1, CBR3, CYC1 MCL1 1190/4885MAPK1 1056/4885CA1 1831/4885
US-12534456-B2 Heterocyclyl pyridines as novel fungicides CBR1, CBR3, NOX1 MCL1 1393/4885MAPK1 855/4885CA1 868/4885
US-20190233444-A1 TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES PIK3C3, ERG28, DDT MCL1 1244/4885MAPK1 2267/4885CA1 2689/4885
US-20190335753-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES GABBR1, DPM1, CYP51A1 MCL1 1971/4885MAPK1 2379/4885CA1 4147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.