Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.59 |
| ▸ | SHBG | P04278 | 4/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.59 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143178 | 0.88 | NR3C1 (0.74) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL4546 | 0.88 | NR3C1 (0.74) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL11156797 | 0.83 | ALDH1A1 (0.71) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL11156788 | 0.83 | ALDH1A1 (0.71) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL8903198 | 0.80 | NR3C1 (0.79) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL607348 | 0.80 | NR3C1 (0.79) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL11638959 | 0.80 | NR3C1 (0.68) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| SCHEMBL11638969 | 0.80 | NR3C1 (0.68) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| Fludrocortisone SCHEMBL23975175 | 0.79 | NR3C1 (1.00) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 | |
| Fludrocortisone SCHEMBL10598529 | 0.79 | NR3C1 (1.00) | CYP2C19ALDH1A1MAPK1NR3C1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9638703-B2 | Quantification of glucocorticoids in fish scales as biomarkers for chronic stress | UNIVERSITEIT GENT (BE) | 2017-05-02 | — | — | US | disclosed |