Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 3/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19139063 | 0.88 | SIRT5 (0.54) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL22920564 | 0.87 | SIRT1 (0.56) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL18800100 | 0.84 | SIRT5 (0.62) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL19117856 | 0.84 | SIRT5 (0.51) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL21303704 | 0.84 | SIRT1 (0.56) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL4567600 | 0.84 | SIRT1 (0.56) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL19113439 | 0.83 | SIRT5 (0.53) | SIRT5FOLH1ALBSIRT6SIRT1 | |
| SCHEMBL24709112 | 0.80 | FOLH1 (0.48) | SIRT5FOLH1ALBADRA1AGNPAT | |
| SCHEMBL8280997 | 0.80 | FOLH1 (0.48) | SIRT5FOLH1ALBADRA1AGNPAT | |
| SCHEMBL14947853 | 0.79 | SIRT6 (0.50) | SIRT5FOLH1ALBSIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637773-B2 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties | ENZO LIFE SCIENCES, INC. (US) | 2017-05-02 | — | — | US | disclosed |