Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16114881 | 0.73 | DNMT1 (0.44) | BCHEACHEALDH1A1LMNAMAPT | |
| SCHEMBL455943 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL29418178 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL29418125 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL4915508 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL31633516 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31439257 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTDNMT1CYP3A4 | |
| SCHEMBL31633515 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL25019358 | 0.70 | NSD2 (0.43) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL30791444 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238200-A1 | CHIRAL N-SUBSTITUTED ALLYLIC AMINE COMPOUNDS | UNIVERSITY OF LOUISIANA AT LAFAYETTE | 2021-08-05 | — | — | US | disclosed |
| US-11021494-B2 | Chiral N-substituted allylic amine compounds | UNIVERSITY OF LOUISIANA AT LAFAYETTE (US) | 2021-06-01 | — | — | US | disclosed |
| US-20190106440-A1 | COMPOSITION OF MATTER | UNIVERSITY OF LOUISIANA AT LAFAYETTE | 2019-04-11 | — | — | US | disclosed |
| US-9637503-B2 | Composition of matter | UNIVERSITY OF LOUISIANA AT LAFAYETTE (US) | 2017-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238200-A1 | CHIRAL N-SUBSTITUTED ALLYLIC AMINE COMPOUNDS | HNMT, NNMT, PNMT | BCHE 65/4885ACHE 179/4885ALDH1A1 501/4885 |
| US-11021494-B2 | Chiral N-substituted allylic amine compounds | HNMT, NNMT, PNMT | BCHE 76/4885ACHE 192/4885ALDH1A1 524/4885 |
| US-20190106440-A1 | COMPOSITION OF MATTER | HNMT, TPMT, NNMT | BCHE 73/4885ACHE 86/4885ALDH1A1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.