Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801082 | 0.82 | PPARG (0.43) | KMT2ABRD4HTTALDH1A1NPC1 | |
| SCHEMBL1649414 | 0.80 | CYP19A1 (0.38) | CYP19A1CYP11B1CYP11B2TUBB4ATUBB | |
| SCHEMBL18801417 | 0.76 | KMT2A (0.44) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL18801282 | 0.75 | KMT2A (0.43) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL18801137 | 0.74 | KMT2A (0.43) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL18801059 | 0.73 | KMT2A (0.42) | KMT2AHTTALDH1A1NPC1RAB9A | |
| SCHEMBL18801035 | 0.71 | KMT2A (0.43) | CYP3A4KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL18801149 | 0.71 | L3MBTL1 (0.39) | AAK1KMT2AHTTALDH1A1NPC1 | |
| SCHEMBL18801280 | 0.71 | KMT2A (0.39) | CYP3A4KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL1649341 | 0.70 | METAP2 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |