SCHEMBL188081

SCHEMBL188081

CC(CC(N)C(=O)O)C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.58
SLC1A2 P43004 7/20 0.52
SLC1A1 P43005 7/20 0.52
SLC1A3 P43003 6/20 0.52
GRIK1 P39086 11/20 0.44
GRIK2 Q13002 8/20 0.44
GRIA4 P48058 3/20 0.42
GRIK3 Q13003 3/20 0.42
GRIK5 Q16478 3/20 0.42
GRIA2 P42262 2/20 0.41
GRIA1 P42261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22957032 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL4420457 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL4419214 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL4421189 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL4421181 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL188082 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL23391696 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
SCHEMBL20641484 1.00 SLC7A5 (0.58) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
Hydrochloric Acid SCHEMBL23391711 0.98 SLC7A5 (0.56) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1
Hydrochloric Acid SCHEMBL23391697 0.98 SLC7A5 (0.56) SLC7A5SLC1A2SLC1A1SLC1A3GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
EP-4021475-A1 PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF Arizona Board of Regents on behalf of the University of Arizona (US) 2022-07-06 EP claimed
WO-2021042064-A1 PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2021-03-04 WO claimed
US-20210032304-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2021-02-04 US claimed
EP-3752174-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF University of Florida Research Foundation, Incorporated (US) 2020-12-23 EP claimed
CN-111936157-A Fibroblast growth factor analogs and uses thereof 佛罗里达大学研究基金会 2020-11-13 CN claimed
EP-2994154-B1 ANTIMICROBIAL PEPTIDE ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2020-02-26 EP claimed
EP-1017358-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-07-12 EP claimed
WO-1999046272-A1 SERINE PEPTIDASE MODULATORS FONDATECH BENELUX N.V. (BE) 1999-09-16 WO claimed
US-5939458-A APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN GILLETTE COMPANY, THE 1999-08-17 US claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
US-5744331-A AEROBIC FERMENTATION OF BACTERIA BELONGING TO THE GENUS ESCHERICHIA KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-04-28 US claimed
US-5543396-A Proline phosphonate derivatives GEORGIA TECH RESEARCH CORP. (US) 1996-08-06 US claimed
CN-1127787-A Method for producing L-leucine KYOWA HAKKO KOGYO KK (JP) 1996-07-31 CN claimed
US-5514694-A ENZYME INHIBITORS GEORGIA TECH RESEARCH CORP (US) 1996-05-07 US claimed
EP-0698668-A1 Process for producing L-leucine KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-02-28 EP claimed
WO-1995029691-A1 PROLINE PHOSPHONATE DERIVATIVES GEORGIA TECH RESEARCH CORPORATION (US) 1995-11-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM SLC7A5 1166/4885SLC1A2 2114/4885SLC1A1 2654/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC SLC7A5 378/4885SLC1A2 1423/4885SLC1A1 786/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM SLC7A5 1166/4885SLC1A2 2114/4885SLC1A1 2654/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT SLC7A5 64/4885SLC1A2 271/4885SLC1A1 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.