Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.50 |
| ▸ | CNR1 | P21554 | 11/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270907 | 0.89 | CNR1 (0.53) | CNR2CNR1MPOALDH1A1 | |
| SCHEMBL17173645 | 0.82 | CNR1 (0.46) | CNR2CNR1 | |
| SCHEMBL17177770 | 0.81 | TP53 (0.59) | TP53L3MBTL1ALDH1A1CYP1A2GAA | |
| SCHEMBL18811870 | 0.80 | CNR2 (0.38) | CNR2CNR1TP53L3MBTL1 | |
| SCHEMBL12859150 | 0.78 | LMNA (0.39) | CNR2CNR1TP53L3MBTL1MPO | |
| SCHEMBL17196467 | 0.78 | L3MBTL1 (0.44) | CNR2CNR1TP53L3MBTL1MPO | |
| SCHEMBL18695215 | 0.77 | L3MBTL1 (0.46) | CNR2CNR1TP53L3MBTL1MPO | |
| SCHEMBL21089562 | 0.76 | L3MBTL1 (0.42) | CNR2CNR1TP53L3MBTL1MPO | |
| SCHEMBL18695253 | 0.76 | TP53 (0.45) | CNR2CNR1TP53L3MBTL1MPO | |
| SCHEMBL22637870 | 0.75 | TP53 (0.50) | CNR2CNR1TP53L3MBTL1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926302-B2 | Heteroaryl substituted heterocyclyl sulfones | Grünenthal GmbH (DE) | 2018-03-27 | — | — | US | disclosed |
| US-9879000-B2 | Heteroaryl substituted heterocyclyl sulfones | Grünenthal GmbH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20170121314-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121314-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | TRPV1, CACNA1B, CACNA1C | CNR2 100/4885CNR1 115/4885TP53 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.