Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089562 | 0.88 | L3MBTL1 (0.42) | L3MBTL1TP53LMNAMPOALDH1A1 | |
| SCHEMBL18695215 | 0.86 | L3MBTL1 (0.46) | L3MBTL1TP53LMNAMPOALDH1A1 | |
| SCHEMBL17177770 | 0.81 | TP53 (0.59) | L3MBTL1TP53LMNAALDH1A1HPGD | |
| SCHEMBL12871860 | 0.80 | MPO (0.45) | L3MBTL1TP53LMNAMPOALDH1A1 | |
| SCHEMBL28311236 | 0.78 | MPO (0.38) | MPOALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL18811869 | 0.78 | CNR2 (0.50) | L3MBTL1TP53MPOALDH1A1HPGD | |
| SCHEMBL18695214 | 0.78 | TP53 (0.44) | L3MBTL1TP53LMNAALDH1A1HPGD | |
| SCHEMBL18695253 | 0.76 | TP53 (0.45) | L3MBTL1TP53LMNAMPOALDH1A1 | |
| SCHEMBL22637870 | 0.75 | TP53 (0.50) | L3MBTL1TP53LMNAALDH1A1HPGD | |
| SCHEMBL9608955 | 0.74 | ALDH1A1 (0.40) | LMNAALDH1A1KDM4EPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158427-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2015-10-22 | — | — | WO | disclosed |