Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 2/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891389 | 0.88 | TRPM8 (0.52) | TRPM8AAK1HPGD | |
| SCHEMBL10155488 | 0.88 | TRPM8 (0.52) | TRPM8AAK1HPGD | |
| SCHEMBL10155415 | 0.74 | TRPM8 (0.48) | TRPM8HPGDSMN1; SMN2RXFP1POLB | |
| SCHEMBL17923432 | 0.74 | TRPM8 (0.48) | TRPM8HPGDSMN1; SMN2RXFP1POLB | |
| SCHEMBL10155495 | 0.70 | TRPM8 (0.55) | TRPM8HPGD | |
| SCHEMBL2963768 | 0.67 | MAP2K2 (0.45) | HPGDSMN1; SMN2POLBMAP2K2MAP2K1 | |
| SCHEMBL2963771 | 0.66 | HTR7 (0.36) | — | |
| SCHEMBL2628634 | 0.62 | TRPM8 (0.70) | TRPM8HPGDSMN1; SMN2RXFP1FPR2 | |
| SCHEMBL18662582 | 0.61 | TRPM8 (0.77) | TRPM8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21676991 | 0.60 | TRPM8 (0.52) | TRPM8HPGDSMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119639-A1 | COMPOSITIONS FOR DEPOSITION ON BIOLOGICAL SURFACES | PROCTER & GAMBLE (US) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119639-A1 | COMPOSITIONS FOR DEPOSITION ON BIOLOGICAL SURFACES | CUTA, TAS2R40, TAS2R20 | TRPM8 54/4885AAK1 2534/4885HPGD 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.