Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250185 | 0.88 | CES2 (0.56) | CES2LMNACES1BLMNPSR1 | |
| SCHEMBL18813637 | 0.85 | TAS1R3 (0.56) | CES2LMNACES1SLC6A2SLC6A4 | |
| SCHEMBL6473954 | 0.85 | NPSR1 (0.54) | CES2LMNACES1BLMNPSR1 | |
| SCHEMBL8146034 | 0.84 | LMNA (0.53) | CES2LMNACES1TAS1R3TAS1R1 | |
| SCHEMBL28601945 | 0.83 | TSHR (0.66) | LMNASLC6A2SLC6A4SLC6A3TAS1R3 | |
| SCHEMBL28233452 | 0.83 | TSHR (0.66) | LMNASLC6A2SLC6A4SLC6A3TAS1R3 | |
| SCHEMBL9056162 | 0.83 | CES2 (0.61) | CES2LMNACES1KDM4EALDH1A1 | |
| Acrylic Acid SCHEMBL10353518 | 0.81 | CES2 (0.47) | CES2LMNACES1BLMNPSR1 | |
| SCHEMBL2040575 | 0.79 | CES2 (0.56) | CES2LMNACES1BLMNPSR1 | |
| SCHEMBL18009401 | 0.79 | FDPS (0.48) | CES2LMNACES1BLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |