Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250188 | 0.88 | CA12 (0.57) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL18813636 | 0.85 | CES2 (0.53) | TAS1R3TAS1R1CES2LMNACES1 | |
| SCHEMBL8148527 | 0.84 | LMNA (0.60) | TAS1R3TAS1R1CES2LMNACES1 | |
| SCHEMBL9057035 | 0.83 | CES2 (0.61) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL2040577 | 0.79 | LMNA (0.56) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL18009402 | 0.79 | TSHR (0.47) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL6335127 | 0.78 | TAS1R3 (0.56) | TAS1R3TAS1R1LMNAALDH1A1KDM4E | |
| SCHEMBL24054890 | 0.78 | CTNNB1 (0.57) | TAS1R3TAS1R1LMNAALDH1A1KDM4E | |
| SCHEMBL11273619 | 0.77 | LMNA (0.53) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL25616782 | 0.77 | CTNNB1 (0.46) | TAS1R3TAS1R1CES2LMNACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |