Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040575 | 0.88 | CES2 (0.56) | LMNACES2CES1ALDH1A1CYP1A2 | |
| SCHEMBL11706382 | 0.87 | MAPK1 (0.50) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL28250188 | 0.84 | CA12 (0.57) | LMNACES2CES1ALDH1A1CYP1A2 | |
| SCHEMBL17785925 | 0.83 | LMNA (0.46) | LMNACES2CES1ALDH1A1MEN1 | |
| SCHEMBL31250051 | 0.83 | LMNA (0.46) | LMNACES2CES1ALDH1A1MEN1 | |
| SCHEMBL9530939 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TNFRSF1AMEN1KMT2A | |
| SCHEMBL139043 | 0.81 | LMNA (0.59) | LMNACES2CES1ALDH1A1MEN1 | |
| Bicarbonate SCHEMBL2779583 | 0.79 | LMNA (0.58) | LMNACES2CES1ALDH1A1MEN1 | |
| SCHEMBL10429201 | 0.79 | SLC6A5 (0.50) | LMNATNFRSF1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18813637 | 0.79 | TAS1R3 (0.56) | LMNACES2CES1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177238-B | Synthetic 3,4-bis-(3,4,5-trimethoxyphenyl)-2, the method for 5-diphenyl cyclopentadienone | SHANDONG UNIVERSITY (CN) | 2016-05-25 | — | — | CN | disclosed |
| WO-2011068379-A2 | HIGHLY SOLUBLE AND HIGHLY DURABLE NEAR-INFRARED ABSORBING COMPOUND AND A NEAR-INFRARED ABSORBING MATERIAL COMPRISING THE SAME | (주) 경인양행 (KR) | 2011-06-09 | — | — | WO | disclosed |