Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.59 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091018 | 0.86 | GPR52 (0.47) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9091138 | 0.86 | GPR52 (0.47) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28340415 | 0.85 | GPR52 (0.59) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18226975 | 0.82 | TUBB4A (0.62) | GPR52TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27574463 | 0.81 | MAPT (0.64) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18813647 | 0.81 | FOLH1 (0.47) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7864455 | 0.80 | BCAT2 (0.59) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28993895 | 0.79 | RECQL (0.59) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31521259 | 0.78 | BCAT2 (0.57) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5180034 | 0.78 | BCAT2 (0.57) | GPR52BCAT2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676693-B2 | Bulky ligands and metal compounds comprising bulky ligands | MARSHAK MICHAEL PESEK (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170121263-A1 | BULKY LIGANDS AND METAL COMPOUNDS COMPRISING BULKY LIGANDS | MARSHAK MICHAEL PESEK (US) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121263-A1 | BULKY LIGANDS AND METAL COMPOUNDS COMPRISING BULKY LIGANDS | ACACB, ACACA, ZKSCAN2 | GPR52 3387/4885BCAT2 939/4885MEN1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.