Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078263 | 0.83 | P2RX7 (0.63) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL12230958 | 0.81 | P2RX7 (0.61) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL71547 | 0.81 | KDM4E (0.63) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29496114 | 0.81 | P2RX7 (0.61) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29651292 | 0.81 | KDM4E (0.63) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL70978 | 0.81 | P2RX7 (0.61) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL7715770 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL7642752 | 0.79 | P2RX7 (0.59) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL724087 | 0.79 | P2RX7 (0.65) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1646832 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090117032-A1 | Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque | THE GENERAL HOSPITAL CORPORATION (US) | 2009-05-07 | — | — | US | claimed |
| WO-2006091506-A2 | NEUROPEPTIDE Y4 RECEPTOR AGONISTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-08-31 | — | — | WO | claimed |
| EP-1011738-A1 | IMAGING AGENTS FOR EARLY DETECTION OF CARDIOVASCULAR PLAQUE | THE GENERAL HOSPITAL CORPORATION (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1999012579-A1 | IMAGING AGENTS FOR EARLY DETECTION AND MONITORING OF CARDIOVASCULAR PLAQUE | THE GENERAL HOSPITAL CORPORATION (US) | 1999-03-18 | — | — | WO | claimed |
| US-20230108636-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | UNIV JOHNS HOPKINS (US) | 2023-04-06 | — | — | US | disclosed |
| US-20210338849-A1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-11-04 | — | — | US | disclosed |
| EP-3231804-B1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-03-03 | — | — | EP | disclosed |
| US-10857247-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | THE GENERAL HOSPITAL CORPORATION (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190261858-A1 | IMAGING METHOD FOR ACUTE LYMPHOBLASTIC LEUKEMIA USING AN IMAGING AGENT AND METHOD OF PRODUCING AN IMAGING AGENT | SATZ STANLEY (US) | 2019-08-29 | — | — | US | disclosed |
| US-10300154-B2 | Anticoagulant derivatives for cardiovascular imaging | ELMALEH DAVID R (US) | 2019-05-28 | — | — | US | disclosed |
| EP-3231804-A1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | The General Hospital Corporation (US) | 2017-10-18 | — | — | EP | disclosed |
| US-20170290931-A1 | ANTICOAGULANT DERIVATIVES FOR CARDIOVASCULAR IMAGING | ELMALEH DAVID R (US) | 2017-10-12 | — | — | US | disclosed |
| WO-1997024146-A1 | CARDIOVASCULAR AND THROMBUS IMAGING AGENTS, METHODS AND KITS | THE GENERAL HOSPITAL CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| US-5641727-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0692482-A2 | 1-pyridyltetrazolinone derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-4980357-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1990-12-25 | — | — | US | disclosed |
| WO-1989001775-A1 | AZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-03-09 | — | — | WO | disclosed |
| EP-0306251-A2 | Azolidinedione derivatives | PFIZER INC. (US) | 1989-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338849-A1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | APP, PSEN1, PSEN2 | P2RX7 1274/4885KDM4E 3295/4885TDP1 1128/4885 |
| US-10300154-B2 | Anticoagulant derivatives for cardiovascular imaging | F3, TFPI, SERPINC1 | P2RX7 741/4885KDM4E 2306/4885TDP1 1442/4885 |
| US-20230108636-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | SLC26A4, SLC26A3, SLC10A2 | P2RX7 387/4885KDM4E 4800/4885TDP1 4403/4885 |
| US-10857247-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | APP, PSEN1, PSEN2 | P2RX7 1274/4885KDM4E 3295/4885TDP1 1128/4885 |
| US-20170290931-A1 | ANTICOAGULANT DERIVATIVES FOR CARDIOVASCULAR IMAGING | F3, TFPI, SERPINC1 | P2RX7 741/4885KDM4E 2306/4885TDP1 1442/4885 |
| US-20190261858-A1 | IMAGING METHOD FOR ACUTE LYMPHOBLASTIC LEUKEMIA USING AN IMAGING AGENT AND METHOD OF PRODUCING AN IMAGING AGENT | MCL1, FLI1, BCL3 | P2RX7 4702/4885KDM4E 2860/4885TDP1 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.