Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795370 | 0.93 | POLB (0.37) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL19159115 | 0.89 | POLB (0.36) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL21693411 | 0.88 | POLB (0.32) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL22842235 | 0.86 | POLB (0.35) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL21115722 | 0.86 | POLB (0.37) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL18509368 | 0.83 | THRB (0.35) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL21087449 | 0.83 | POLB (0.35) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL27423567 | 0.82 | POLB (0.38) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL25795454 | 0.81 | POLB (0.36) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL18476298 | 0.81 | POLB (0.37) | POLBAPEX1HTTTDP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312909-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-04-26 | — | — | US | disclosed |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | GMBH, MERCK PATENT (DE) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312909-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, LCP1, MAP1LC3C | POLB 3739/4885APEX1 3526/4885HTT 1643/4885 |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LCP1, MAP1LC3C | POLB 3879/4885APEX1 3407/4885HTT 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.