Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.31 |
| ▸ | PNLIP | P16233 | 3/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18844463 | 0.99 | FGFR1 (0.39) | FGFR1SRCPDK2ADRB2TP53 | |
| Bicarbonate SCHEMBL18824162 | 0.92 | FGFR1 (0.37) | FGFR1SRCTP53MEN1NPC1 | |
| Bicarbonate SCHEMBL21046372 | 0.92 | FGFR1 (0.35) | FGFR1SRCGAAMEN1NPC1 | |
| Iodide SCHEMBL30731322 | 0.89 | LTA4H (0.39) | FGFR1TP53GAANPC1RAB9A | |
| SCHEMBL17916653 | 0.88 | LTA4H (0.40) | FGFR1TP53GAANPC1RAB9A | |
| SCHEMBL25860237 | 0.85 | CARM1 (0.34) | FGFR1ADRB2SIGMAR1 | |
| Iodide SCHEMBL21046358 | 0.85 | CASR (0.35) | ALDH2MAOAMAOB | |
| SCHEMBL21046373 | 0.85 | HTT (0.36) | TP53GAAMEN1NPC1RAB9A | |
| Bicarbonate SCHEMBL17911341 | 0.83 | TP53 (0.39) | TP53 | |
| Iodide SCHEMBL22366566 | 0.82 | ADRB2 (0.33) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2021-05-18 | — | — | US | disclosed |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2019-06-06 | — | — | US | disclosed |
| WO-2017075704-A1 | METHODS OF FORMING CARBENE-FUNCTIONALIZED COMPOSITE MATERIALS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | VCL, CHN2, CA3 | FGFR1 4725/4885SRC 2126/4885PDK2 1488/4885 |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | VCL, CHN2, CA3 | FGFR1 4725/4885SRC 2126/4885PDK2 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.