Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.62 |
| ▸ | MLYCD | O95822 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.57 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.57 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.57 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126678 | 0.88 | ROCK2 (0.64) | EPHX2ROCK2ROCK1KMT2AMEN1 | |
| SCHEMBL5665029 | 0.87 | EPHX2 (0.76) | EPHX2ROCK2ROCK1KMT2AMEN1 | |
| SCHEMBL31078105 | 0.84 | RORC (0.77) | RORCEPHX2MLYCDKMT2AMEN1 | |
| SCHEMBL5314168 | 0.84 | RORC (0.77) | RORCMLYCDKMT2AMEN1NPC1 | |
| SCHEMBL13167592 | 0.82 | NAMPT (0.82) | ROCK2ROCK1KMT2AMEN1LMNA | |
| SCHEMBL11161284 | 0.81 | ROCK2 (0.66) | EPHX2ROCK2ROCK1KMT2AMEN1 | |
| SCHEMBL29362556 | 0.80 | ROCK2 (0.73) | ROCK2ROCK1KMT2AMEN1LMNA | |
| SCHEMBL9031269 | 0.80 | ROCK2 (0.73) | ROCK2ROCK1KMT2AMEN1LMNA | |
| SCHEMBL6122991 | 0.78 | ABL1 (0.76) | ROCK2ROCK1KMT2ANPC1RAB9A | |
| SCHEMBL4880524 | 0.78 | RORC (1.00) | RORCEPHX2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245633-A1 | ROR Gamma Agonists as Enhancers of Protective Immunity | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-07-25 | — | — | US | disclosed |
| WO-2017079120-A1 | ROR GAMMA AGONISTS AS ENHANCERS OF PROTECTIVE IMMUNITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245633-A1 | ROR Gamma Agonists as Enhancers of Protective Immunity | RORC, RORB, RORA | RORC 1/4885EPHX2 3446/4885ROCK2 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.