Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.84 |
| ▸ | PDE5A | O76074 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | GLA | P06280 | 1/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | CDC42 | P60953 | 1/20 | 0.83 |
| ▸ | ATM | Q13315 | 1/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.83 |
| ▸ | MMP2 | P08253 | 3/20 | 0.82 |
| ▸ | MMP9 | P14780 | 3/20 | 0.82 |
| ▸ | CA1 | P00915 | 4/20 | 0.76 |
| ▸ | CA2 | P00918 | 4/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18827580 | 0.93 | L3MBTL1 (0.82) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL12494043 | 0.91 | L3MBTL1 (1.00) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL18827566 | 0.90 | PTGS2 (0.89) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL18827569 | 0.89 | PTGS2 (0.92) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL18826383 | 0.88 | PTGS2 (0.85) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL15197341 | 0.86 | CA1 (1.00) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL28808747 | 0.86 | MMP2 (0.81) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL5564567 | 0.84 | L3MBTL1 (1.00) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL18826391 | 0.83 | L3MBTL1 (0.76) | L3MBTL1PDE5AKDM4EALDH1A1GLA | |
| SCHEMBL15197347 | 0.83 | CA1 (1.00) | L3MBTL1PDE5AKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |