Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.81 |
| ▸ | MMP9 | P14780 | 4/20 | 0.81 |
| ▸ | CA2 | P00918 | 10/20 | 0.73 |
| ▸ | CA1 | P00915 | 8/20 | 0.73 |
| ▸ | ACHE | P22303 | 5/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | PDE5A | O76074 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CDC42 | P60953 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18826382 | 0.86 | L3MBTL1 (0.84) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL28810693 | 0.85 | L3MBTL1 (0.79) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL18826383 | 0.84 | PTGS2 (0.85) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL18827580 | 0.83 | L3MBTL1 (0.82) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL27944763 | 0.81 | L3MBTL1 (0.69) | MMP2MMP9CA2CA1L3MBTL1 | |
| SCHEMBL18827566 | 0.80 | PTGS2 (0.89) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL27954385 | 0.79 | CA2 (0.76) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL12494043 | 0.79 | L3MBTL1 (1.00) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL18826380 | 0.77 | PTGS2 (0.80) | MMP2MMP9CA2CA1ACHE | |
| SCHEMBL15197341 | 0.76 | CA1 (1.00) | MMP2MMP9CA2CA1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664786-A | Synthesis method of dihydro-pyrazole sulfonamide derivatives of salicylaldehydes and application of dihydro-pyrazole sulfonamide derivatives to preparation of anticancer drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |