Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.54 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 4/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561415 | 0.88 | LPAR1 (0.69) | LPAR1GPR132 | |
| SCHEMBL18832654 | 0.87 | LPAR1 (0.63) | LPAR1NOX1HDAC1 | |
| SCHEMBL18832667 | 0.86 | LPAR1 (0.53) | LPAR1GPR132ALOX5SIRT2F10 | |
| SCHEMBL18832675 | 0.84 | LPAR1 (0.61) | LPAR1GPR132NOX1SIRT2 | |
| SCHEMBL18832661 | 0.83 | LPAR1 (0.60) | LPAR1 | |
| SCHEMBL18832662 | 0.83 | LPAR1 (0.60) | LPAR1GPR132SIRT2 | |
| SCHEMBL18832657 | 0.82 | LPAR1 (0.79) | LPAR1GPR132NOX1SIRT2F10 | |
| SCHEMBL18832664 | 0.82 | LPAR1 (0.58) | LPAR1GPR132SIRT2 | |
| SCHEMBL18832658 | 0.82 | LPAR1 (0.58) | LPAR1GPR132SCN9A | |
| SCHEMBL18832678 | 0.81 | LPAR1 (0.63) | LPAR1NOX1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |