Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105398 | 0.90 | MEN1 (0.50) | ADORA3SMN1; SMN2KMT2AMEN1BRD4 | |
| SCHEMBL21499640 | 0.90 | MDM2 (0.38) | ADORA3KMT2AF11ALDH1A1NPSR1 | |
| SCHEMBL21316348 | 0.88 | ALDH1A1 (0.40) | ADORA3SMN1; SMN2KMT2AMEN1BRD4 | |
| SCHEMBL21316344 | 0.82 | P2RX3 (0.40) | ADORA3SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL18835230 | 0.82 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL18835341 | 0.81 | TRPC4 (0.41) | ADORA3SMN1; SMN2KMT2AMEN1PCSK9 | |
| SCHEMBL19505500 | 0.80 | TRPC5 (0.50) | ADORA3SMN1; SMN2KMT2AMEN1PCSK9 | |
| SCHEMBL18834975 | 0.80 | KDM4E (0.39) | ADORA3SMN1; SMN2ALDH1A1PDE4APDE4B | |
| SCHEMBL19375051 | 0.79 | MDM2 (0.38) | LMNAMAPTTP53 | |
| SCHEMBL21499716 | 0.79 | PDE4A (0.38) | ADORA3SMN1; SMN2KMT2AMEN1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |