Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RGS4 | P49798 | 1/20 | 0.33 |
| ▸ | RGS8 | P57771 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316348 | 0.85 | ALDH1A1 (0.40) | TP53P2RX7LMNAMAPT | |
| SCHEMBL19505584 | 0.84 | P2RX7 (0.39) | P2RX3P2RX7RGS4RGS8 | |
| SCHEMBL18834622 | 0.84 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL18835230 | 0.81 | ALDH1A1 (0.41) | TP53P2RX3P2RX7LMNAMAPT | |
| SCHEMBL20432069 | 0.80 | TRPC5 (0.36) | MDM2TP53P2RX3P2RX7LMNA | |
| SCHEMBL19505582 | 0.80 | TRPC5 (0.37) | MDM2P2RX3P2RX7LMNAMAPT | |
| SCHEMBL19375039 | 0.80 | RAB9A (0.36) | MDM2TP53P2RX3P2RX7LMNA | |
| SCHEMBL21499640 | 0.80 | MDM2 (0.38) | MDM2TP53P2RX3 | |
| SCHEMBL18834436 | 0.78 | PPARG (0.36) | P2RX3P2RX7LMNAMAPTL3MBTL1 | |
| SCHEMBL20432432 | 0.77 | PDE5A (0.37) | P2RX3RGS4RGS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |