Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432069 | 0.93 | TRPC5 (0.36) | KDM4EALDH1A1HPGDADORA3TRPC5 | |
| SCHEMBL18835033 | 0.89 | USP1 (0.39) | HPGDADORA3TRPC5TSHRPDE5A | |
| SCHEMBL18834470 | 0.87 | TRPC5 (0.35) | ALDH1A1TRPC5TSHRGAAPDE4D | |
| SCHEMBL19375039 | 0.83 | RAB9A (0.36) | KDM4EALDH1A1ADORA3TSHRPOLB | |
| SCHEMBL22105398 | 0.82 | MEN1 (0.50) | KDM4EALDH1A1HPGDADORA3POLB | |
| SCHEMBL21316348 | 0.81 | ALDH1A1 (0.40) | KDM4EALDH1A1ADORA3TRPC5TSHR | |
| SCHEMBL18834436 | 0.81 | PPARG (0.36) | KDM4EALDH1A1ADORA3TSHRPOLB | |
| SCHEMBL18834435 | 0.80 | MAPT (0.39) | ALDH1A1HPGDADORA3TRPC5TSHR | |
| SCHEMBL21499716 | 0.79 | PDE4A (0.38) | ALDH1A1ADORA3TSHRPOLBGAA | |
| SCHEMBL21316344 | 0.79 | P2RX3 (0.40) | KDM4EALDH1A1HPGDADORA3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |