SCHEMBL1883689

SCHEMBL1883689

Cc1cn([C@H]2C[C@H](O)[C@@H](CSC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1883691 1.00 TK1 (0.55) TK1
SCHEMBL7908347 0.93 TK1 (0.51) TK1
Doxribtimine SCHEMBL8640450 0.84 TK1 (0.53) TK1
SCHEMBL10446716 0.82 POLB (0.58) TK1
SCHEMBL6334503 0.82 POLB (0.58) TK1
SCHEMBL1727320 0.82 POLB (0.58) TK1
SCHEMBL8655889 0.82 DUT (0.71)
SCHEMBL1727537 0.82 POLB (0.58) TK1
SCHEMBL8655891 0.82 DUT (0.71)
SCHEMBL6077816 0.82 POLB (0.58) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952587-B1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS INC (US) 2023-07-05 EP disclosed
US-20180334729-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION Roche Sequencing Solutions, Inc. 2018-11-22 US disclosed
US-9920386-B2 High throughput nucleic acid sequencing by expansion STRATOS GENOMICS, INC. (US) 2018-03-20 US disclosed
US-20160208344-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION Roche Sequencing Solutions, Inc. 2016-07-21 US disclosed
EP-2952587-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION Stratos Genomics Inc. (US) 2015-12-09 EP disclosed
EP-2171088-B1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS INC (US) 2015-10-14 EP disclosed
US-20130172197-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS, INC. (US) 2013-07-04 US disclosed
US-8349565-B2 High throughput nucleic acid sequencing by expansion STRATOS GENOMICS, INC. (US) 2013-01-08 US disclosed
US-8324360-B2 High throughput nucleic acid sequencing by expansion STRATOS GENOMICS, INC. (US) 2012-12-04 US disclosed
US-20110251079-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS, INC. (US) 2011-10-13 US disclosed
WO-2008157696-A2 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS INC. (US) 2008-12-24 WO disclosed
US-20060040282-A1 Oligonucleotide sizing using cleavable primers SEQUENOM, INC. (US) 2006-02-23 US disclosed
US-6949633-B1 Primers useful for sizing nucleic acids SEQUENOM, INC. (US) 2005-09-27 US disclosed
EP-0828855-B1 Oligonucleotide sizing using cleavable primers STANFORD RES INST INT (US) 1999-12-15 EP disclosed
US-5830655-A DETERMINATION THE SIZE OF PRIMER EXTENSION SRI INTERNATIONAL (US) 1998-11-03 US disclosed
US-5807837-A ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL SANKYO COMPANY, LIMITED (JP) 1998-09-15 US disclosed
EP-0828855-A1 OLIGONUCLEOTIDE SIZING USING CLEAVABLE PRIMERS SRI INTERNATIONAL (US) 1998-03-18 EP disclosed
US-5700642-A HYBRIDIZING PRIMER WITH COMPLEMENTARY TARGET NUCLEIC ACID, ENZYMATICALLY EXTENDING PRIMER TO GENERATE POLYNUCLEOTIDE MIXTURE, IMMOBILIZATION, CLEAVING TO RELEASE EXTENSION SEGMENT AND MEASUREMENT BY MASS SPECTROMETRY SRI INTERNATIONAL (US) 1997-12-23 US disclosed
US-5674856-A TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS SANKYO COMPANY, LIMITED (JP) 1997-10-07 US disclosed
WO-1996037630-A1 OLIGONUCLEOTIDE SIZING USING CLEAVABLE PRIMERS SRI INTERNATIONAL (US) 1996-11-28 WO disclosed