Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433080 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTMAPK1MAOB | |
| SCHEMBL6981876 | 0.83 | IDO1 (0.40) | ALDH1A1LMNAMAPTMAOBKDM4E | |
| SCHEMBL13505294 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTMAPK1KDM4E | |
| SCHEMBL5146026 | 0.77 | MAPT (0.60) | ALDH1A1LMNAMAPTMAPK1KDM4E | |
| SCHEMBL9900604 | 0.76 | THRB (0.37) | ALDH1A1LMNAMAPTMAPK1MAOB | |
| SCHEMBL13505416 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ETDP1POLB | |
| SCHEMBL6662915 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAMAOBTOP1CES2 | |
| SCHEMBL9278957 | 0.75 | MAOB (0.46) | ALDH1A1LMNAMAPTMAPK1MAOB | |
| SCHEMBL7966000 | 0.75 | MAOB (0.46) | ALDH1A1LMNAMAPTMAPK1MAOB | |
| SCHEMBL13505276 | 0.75 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10287419-B2 | Rubber composition and vulcanization aid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-05-14 | — | — | US | disclosed |
| US-10000453-B2 | Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20170362181-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2017-12-21 | — | — | US | disclosed |
| US-20170130028-A1 | RUBBER COMPOSITION AND VULCANIZATION AID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20170130028-A1 | RUBBER COMPOSITION AND VULCANIZATION AID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362181-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | WASF2, SCO2, SOD1 | ALDH1A1 2424/4885LMNA 3565/4885MAPT 2594/4885 |
| US-10000453-B2 | Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts | WASF2, SOD1, CD274 | ALDH1A1 2403/4885LMNA 3454/4885MAPT 2583/4885 |
| US-10287419-B2 | Rubber composition and vulcanization aid | CCNA1, RCN1, RER1 | ALDH1A1 4162/4885LMNA 354/4885MAPT 4791/4885 |
| US-20170130028-A1 | RUBBER COMPOSITION AND VULCANIZATION AID | CCNA1, RCN1, RER1 | ALDH1A1 4162/4885LMNA 354/4885MAPT 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.