Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141402 | 0.86 | AR (0.33) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL1878747 | 0.81 | LMNA (0.42) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL1878124 | 0.78 | CREBBP (0.37) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL12965849 | 0.74 | AR (0.45) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL14234586 | 0.73 | MAPT (0.39) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL12965982 | 0.72 | AR (0.44) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL11362347 | 0.70 | GAA (0.43) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL19122160 | 0.70 | GAA (0.43) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL15311620 | 0.70 | AR (0.43) | LMNAGAAMAPTCREBBPAR | |
| SCHEMBL19289729 | 0.69 | LMNA (0.49) | LMNAGAAMAPTCREBBPAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| EP-2708223-B1 | DYEING AGENT AND USE FOR SAME | AMANO ENZYME INC (JP) | 2017-02-01 | — | — | EP | disclosed |
| EP-3067041-A1 | METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE | Shisei Chemical Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-9358198-B2 | Dyeing of keratin fibers using indole analogue | AMANO ENZYME INC. (JP) | 2016-06-07 | — | — | US | disclosed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | disclosed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8740994-B2 | Dyeing agent and use for same | AMANO ENZYME INC. (JP) | 2014-06-03 | — | — | US | disclosed |
| EP-2708223-A1 | DYEING AGENT AND USE FOR SAME | Amano Enzyme Inc. (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-20140068875-A1 | DYEING AGENT AND USE FOR SAME | AMANO ENZYME INC (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-2623093-A1 | DYE FOR KERATIN FIBERS USING INDOLE ANALOGUE | Amano Enzyme Inc. (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-6958080-B2 | Compositions for dyeing keratinous fiber | LION CORPORATION (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20050170485-A1 | Culture having phenol oxidase-like activity | MANDOM CORPORATION (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1533371-A1 | CULTURE HAVING PHENOL OXIDASE-LIKE ACTIVITY | Mandom Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |
| US-20030106166-A1 | Compositions for dyeing keratinous fiber | LION CORPORATION (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1234569-A1 | COMPOSITIONS FOR DYEING HORNY FIBERS | Lion Corporation (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-1189576-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | Lion Corporation (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-1142561-A1 | HAIR DYE COMPOSITIONS | Lion Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-1142562-A1 | HAIR DYE COMPOSITIONS | Lion Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001000144-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | LION CORPORATION (JP) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106166-A1 | Compositions for dyeing keratinous fiber | KRT18, LPO, CKMT1A; CKMT1B | LMNA 1860/4885GAA 745/4885MAPT 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.