Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14234586 | 0.86 | MAPT (0.39) | LMNAGAAMAPTFYNEP300 | |
| SCHEMBL12965849 | 0.84 | AR (0.45) | LMNAGAAMAPTEP300TSHR | |
| SCHEMBL12965982 | 0.81 | AR (0.44) | LMNAGAAMAPTEP300TSHR | |
| SCHEMBL1884351 | 0.81 | LMNA (0.40) | LMNAGAAMAPTFYNEP300 | |
| SCHEMBL1878124 | 0.80 | CREBBP (0.37) | LMNAGAAMAPTFYNEP300 | |
| SCHEMBL1878123 | 0.80 | LMNA (0.36) | LMNAGAAMAPTEP300DRD2 | |
| SCHEMBL19289729 | 0.78 | LMNA (0.49) | LMNAGAAMAPTEP300DRD2 | |
| SCHEMBL20156702 | 0.78 | LMNA (0.49) | LMNAGAAMAPTEP300DRD2 | |
| SCHEMBL94115 | 0.75 | ESR2 (0.49) | LMNAGAAMAPTEP300DRD2 | |
| SCHEMBL15311620 | 0.74 | AR (0.43) | LMNAGAAMAPTEP300TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| EP-3463271-A1 | GENTLE AGENTS AND METHODS FOR OXIDATIVE DYEING USING SELECTED DICARBOXYLIC ACIDS | Henkel AG & Co. KGaA (DE) | 2019-04-10 | — | — | EP | disclosed |
| EP-3405169-A1 | PRODUCTS FOR PROTECTING KERATIN FIBRES AND METHOD FOR OXIDATIVE HAIR DYEING | Henkel AG & Co. KGaA (DE) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017207631-A1 | GENTLE AGENTS AND METHODS FOR OXIDATIVE DYEING USING SELECTED DICARBOXYLIC ACIDS | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | WO | disclosed |
| EP-3229770-A1 | HAIR COLOURANTS COMPRISING TETRAAMINOPYRIMIDINE DERIVATES | Henkel AG & Co. KGaA (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2017125191-A1 | PRODUCTS FOR PROTECTING KERATIN FIBRES AND METHOD FOR OXIDATIVE HAIR DYEING | HENKEL AG & CO. KGAA (DE) | 2017-07-27 | — | — | WO | disclosed |
| EP-2708223-B1 | DYEING AGENT AND USE FOR SAME | AMANO ENZYME INC (JP) | 2017-02-01 | — | — | EP | disclosed |
| EP-3067041-A1 | METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE | Shisei Chemical Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |
| WO-2016091455-A1 | HAIR COLOURANTS COMPRISING TETRAAMINOPYRIMIDINE DERIVATES | HENKEL AG & CO. KGAA (DE) | 2016-06-16 | — | — | WO | disclosed |
| US-9358198-B2 | Dyeing of keratin fibers using indole analogue | AMANO ENZYME INC. (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20030106166-A1 | Compositions for dyeing keratinous fiber | LION CORPORATION (JP) | 2003-06-12 | — | — | US | disclosed |
| US-20030074743-A1 | Hair dye composition | LION CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1254650-A2 | Hair dye composition | Kao Corporation (JP) | 2002-11-06 | — | — | EP | disclosed |
| EP-1240890-A1 | HAIR DYE COMPOSITION | Lion Corporation (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1234569-A1 | COMPOSITIONS FOR DYEING HORNY FIBERS | Lion Corporation (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-1189576-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | Lion Corporation (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-1142561-A1 | HAIR DYE COMPOSITIONS | Lion Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-1142562-A1 | HAIR DYE COMPOSITIONS | Lion Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001000144-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | LION CORPORATION (JP) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106166-A1 | Compositions for dyeing keratinous fiber | KRT18, LPO, CKMT1A; CKMT1B | LMNA 1860/4885GAA 745/4885MAPT 1133/4885 |
| US-20030074743-A1 | Hair dye composition | HAAO, GRHPR, CD44 | LMNA 3302/4885GAA 414/4885MAPT 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.