SCHEMBL7141402

SCHEMBL7141402

CC1Nc2cc(O)c(O)cc2C1C.CCc1cc2c(cc1O)NC(C)C2

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.33
PGR P06401 2/20 0.33
NR3C1 P04150 1/20 0.33
NR3C2 P08235 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CREBBP Q92793 1/20 0.32
DRD2 P14416 2/20 0.30
MAOA P21397 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
DRD3 P35462 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
EP300 Q09472 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1884351 0.86 LMNA (0.40) ARPGRLMNAGAAMAPT
SCHEMBL1880683 0.77 AR (0.43) ARPGRNR3C1NR3C2DRD2
Bromide SCHEMBL4626245 0.75 AR (0.42) ARPGRNR3C1NR3C2DRD2
SCHEMBL1878747 0.73 LMNA (0.42) ARPGRLMNAGAAMAPT
SCHEMBL1878124 0.67 CREBBP (0.37) ARPGRLMNAGAAMAPT
SCHEMBL12965849 0.64 AR (0.45) ARPGRLMNAGAAMAPT
SCHEMBL28845154 0.63 ACHE (0.36) GAAMAPTMAOAKDM4ETSHR
SCHEMBL14234586 0.63 MAPT (0.39) ARPGRLMNAGAAMAPT
SCHEMBL12965982 0.62 AR (0.44) ARPGRLMNAGAAMAPT
SCHEMBL11362347 0.60 GAA (0.43) ARPGRLMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030074743-A1 Hair dye composition LION CORPORATION (JP) 2003-04-24 US disclosed
EP-1240890-A1 HAIR DYE COMPOSITION Lion Corporation (JP) 2002-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030074743-A1 Hair dye composition HAAO, GRHPR, CD44 AR 248/4885PGR 1790/4885NR3C1 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.