Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12197451 | 0.87 | DRD2 (0.38) | AOC3DRD2DRD1HTR7HTR2A | |
| SCHEMBL14136635 | 0.81 | AOC3 (0.52) | AOC3DRD2DRD1HTR7HTR2A | |
| SCHEMBL12223409 | 0.79 | KDM4E (0.44) | DRD2DRD1HTR7HTR2AHTR2C | |
| SCHEMBL20040527 | 0.76 | DRD2 (0.37) | AOC3DRD2DRD1HTR7HTR2A | |
| SCHEMBL14125005 | 0.76 | DRD2 (0.40) | AOC3DRD2DRD1HTR7HTR2A | |
| SCHEMBL17431881 | 0.75 | DRD2 (0.42) | AOC3DRD2DRD1MGAMAMY1A | |
| SCHEMBL17429259 | 0.74 | MTNR1B (0.41) | AOC3DRD2DRD1ALDH1A1POLB | |
| SCHEMBL16366159 | 0.71 | DRD2 (0.42) | DRD2DRD1MGAMAMY1AGAA | |
| SCHEMBL12439969 | 0.70 | DRD2 (0.38) | DRD2DRD1HTR2AHTR2CDHODH | |
| SCHEMBL14950291 | 0.68 | AOC3 (0.44) | AOC3DRD2DRD1DHODHPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771386-B2 | Z-selective ring-closing metathesis reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170129910-A1 | Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS | NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129910-A1 | Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS | ZYX, ZDHHC7, ZDHHC2 | AOC3 538/4885DRD2 951/4885DRD1 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.