Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 7/20 | 0.66 |
| ▸ | MPI | P34949 | 9/20 | 0.59 |
| ▸ | PMM2 | O15305 | 8/20 | 0.59 |
| ▸ | PHOSPHO1 | Q8TCT1 | 8/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624454 | 0.79 | G6PD (0.66) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL8372604 | 0.79 | MPI (0.72) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL8373005 | 0.79 | G6PD (1.00) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL8373401 | 0.79 | G6PD (0.72) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL18913005 | 0.79 | G6PD (0.60) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL8371733 | 0.78 | G6PD (0.64) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL18845170 | 0.76 | MPI (0.54) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL1900552 | 0.76 | MPI (0.74) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL24327539 | 0.76 | G6PD (0.60) | G6PDMPIPMM2PHOSPHO1APOBEC3G | |
| SCHEMBL8369510 | 0.76 | G6PD (0.60) | G6PDMPIPMM2PHOSPHO1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190142801-A1 | USE OF SMALL MOLECULES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE TOXICITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-05-16 | — | — | US | disclosed |
| US-10172829-B2 | Use of small molecules for the treatment of clostridium difficile toxicity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-01-08 | — | — | US | disclosed |
| US-20170128420-A1 | USE OF SMALL MOLECULES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE TOXICITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10172829-B2 | Use of small molecules for the treatment of clostridium difficile toxicity | SLC10A2, TCERG1, SBDS | G6PD 4253/4885MPI 4658/4885PMM2 4801/4885 |
| US-20190142801-A1 | USE OF SMALL MOLECULES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE TOXICITY | SLC10A2, TCERG1, SBDS | G6PD 4253/4885MPI 4658/4885PMM2 4801/4885 |
| US-20170128420-A1 | USE OF SMALL MOLECULES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE TOXICITY | SLC10A2, TCERG1, SBDS | G6PD 4253/4885MPI 4658/4885PMM2 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.