SCHEMBL1884690

SCHEMBL1884690

c1cnc(Oc2cccc3ccccc23)c(Oc2cccc3ccccc23)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.48
HPGD P15428 2/20 0.47
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PIN1 Q13526 1/20 0.46
KDM4E B2RXH2 2/20 0.44
KDM1A O60341 1/20 0.44
HTR1B P28222 7/20 0.44
HTR1D P28221 1/20 0.44
CYP3A4 P08684 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
SLC6A4 P31645 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4007155 0.85 LMNA (0.48) TRPA1HPGDMAPTALDH1A1MEN1
SCHEMBL9853606 0.81 F12 (0.52) HPGDMAPTALDH1A1MEN1NPC1
SCHEMBL1369945 0.81 ALDH1A1 (0.45) HPGDMAPTALDH1A1MEN1NPC1
Ethane SCHEMBL10636467 0.80 HTR1B (0.50) HPGDMAPTALDH1A1TDP1KDM4E
SCHEMBL442767 0.80 HTR1B (0.54) HPGDMAPTALDH1A1MEN1RAB9A
SCHEMBL29577853 0.80 HTR1B (0.54) HPGDMAPTALDH1A1MEN1RAB9A
SCHEMBL2784042 0.80 NR4A1 (0.51) HPGDMAPTALDH1A1MEN1POLB
SCHEMBL6213751 0.79 ALDH1A1 (0.50) HPGDMAPTALDH1A1MEN1NPC1
Methane SCHEMBL10959030 0.78 HTR1B (0.52) HPGDMAPTALDH1A1MEN1RAB9A
Lithium SCHEMBL6571336 0.78 HTR1B (0.52) HPGDMAPTALDH1A1MEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084661-A Preparation method of 3-hydroxy alkyl acid ester 万华化学集团股份有限公司 2024-05-28 CN disclosed
US-20130281681-A1 Group 3 Post-Metallocene Complexes Based on Bis(Naphthoxy)Pyridine and Bis(Naphthoxy)ThioPhene Ligands for the Ring-Opening Polymerisation of Polar Cyclic Monomers CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-10-24 US disclosed
US-20130281681-A1 Group 3 Post-Metallocene Complexes Based on Bis(Naphthoxy)Pyridine and Bis(Naphthoxy)ThioPhene Ligands for the Ring-Opening Polymerisation of Polar Cyclic Monomers CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-10-24 US disclosed
US-20130281681-A1 Group 3 Post-Metallocene Complexes Based on Bis(Naphthoxy)Pyridine and Bis(Naphthoxy)ThioPhene Ligands for the Ring-Opening Polymerisation of Polar Cyclic Monomers CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-10-24 US disclosed
US-8519070-B2 Post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the polymerisation of ethylene and alpha-olefins TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-08-27 US disclosed
US-8519070-B2 Post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the polymerisation of ethylene and alpha-olefins TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-08-27 US disclosed
US-8519070-B2 Post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the polymerisation of ethylene and alpha-olefins TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-08-27 US disclosed
US-8436133-B2 Group 3 post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the ring-opening polymerisation of polar cyclic monomers TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-05-07 US disclosed
US-8436133-B2 Group 3 post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the ring-opening polymerisation of polar cyclic monomers TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-05-07 US disclosed
US-8436133-B2 Group 3 post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the ring-opening polymerisation of polar cyclic monomers TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-05-07 US disclosed
US-20110112273-A1 Group 3 Post-Metallocene Complexes Based on Bis(Naphthoxy)Pyridine and Bis(Naphthoxy)ThioPhene Ligands for the Ring-Opening Polymerisation of Polar Cyclic Monomers TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-05-12 US disclosed
CN-101959928-A Group 3 post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the ring-opening polymerisation of polar cyclic monomers TOTAL PETROCHEMICALS RES FELUY 2011-01-26 CN disclosed
CN-101959928-A Group 3 post-metallocene complexes based on bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands for the ring-opening polymerisation of polar cyclic monomers TOTAL PETROCHEMICALS RES FELUY 2011-01-26 CN disclosed
EP-2247641-A1 GROUP 3 POST-METALLOCENE COMPLEXES BASED ON BIS(NAPHTHOXY)PYRIDINE AND BIS(NAPHTHOXY)THIOPHENE LIGANDS FOR THE RING-OPENING POLYMERISATION OF POLAR CYCLIC MONOMERS Total Petrochemicals Research Feluy (BE) 2010-11-10 EP disclosed
EP-2247641-A1 GROUP 3 POST-METALLOCENE COMPLEXES BASED ON BIS(NAPHTHOXY)PYRIDINE AND BIS(NAPHTHOXY)THIOPHENE LIGANDS FOR THE RING-OPENING POLYMERISATION OF POLAR CYCLIC MONOMERS Total Petrochemicals Research Feluy (BE) 2010-11-10 EP disclosed
WO-2009106459-A1 GROUP 3 POST-METALLOCENE COMPLEXES BASED ON BIS(NAPHTHOXY)PYRIDINE AND BIS(NAPHTHOXY)THIOPHENE LIGANDS FOR THE RING-OPENING POLYMERISATION OF POLAR CYCLIC MONOMERS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-09-03 WO disclosed
WO-2009106459-A1 GROUP 3 POST-METALLOCENE COMPLEXES BASED ON BIS(NAPHTHOXY)PYRIDINE AND BIS(NAPHTHOXY)THIOPHENE LIGANDS FOR THE RING-OPENING POLYMERISATION OF POLAR CYCLIC MONOMERS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-09-03 WO disclosed
EP-2093242-A1 Group 3 post-metallocene complexes based on bis (Naphthoxy)pyridine and bis (Naphthoxy) thiophene ligands for the ring-opening polymerisation of polar cyclic monomers Total Petrochemicals Research Feluy (BE) 2009-08-26 EP disclosed
EP-2093242-A1 Group 3 post-metallocene complexes based on bis (Naphthoxy)pyridine and bis (Naphthoxy) thiophene ligands for the ring-opening polymerisation of polar cyclic monomers Total Petrochemicals Research Feluy (BE) 2009-08-26 EP disclosed
EP-2093242-A1 Group 3 post-metallocene complexes based on bis (Naphthoxy)pyridine and bis (Naphthoxy) thiophene ligands for the ring-opening polymerisation of polar cyclic monomers Total Petrochemicals Research Feluy (BE) 2009-08-26 EP disclosed