Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884690 | 0.85 | TRPA1 (0.48) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL4008456 | 0.78 | HTR1A (0.51) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL17913749 | 0.77 | HTR1B (0.44) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL30803798 | 0.77 | HTR1B (0.44) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3878940 | 0.76 | PDE10A (0.43) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL2784042 | 0.76 | NR4A1 (0.51) | LMNAMAPTKDM4EHPGDMEN1 | |
| SCHEMBL6213751 | 0.75 | ALDH1A1 (0.50) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL4007377 | 0.75 | HPGD (0.49) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4008138 | 0.74 | HTR1A (0.54) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4009870 | 0.74 | HTR1A (0.54) | LMNASMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |