Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | CHKA | P35790 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29980540 | 0.93 | ADRA2C (0.34) | HRH4HTR3A | |
| SCHEMBL18639230 | 0.86 | ADRA2C (0.32) | HRH4 | |
| SCHEMBL17934702 | 0.81 | — | — | |
| SCHEMBL18052758 | 0.75 | ALDH1A1 (0.38) | HRH4HTR3A | |
| SCHEMBL20780839 | 0.74 | — | — | |
| SCHEMBL12663101 | 0.74 | CHRNA7 (0.42) | LMNA | |
| SCHEMBL31696522 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL13650809 | 0.71 | ALDH1A1 (0.38) | NCF1LMNAHTR3A | |
| SCHEMBL30425332 | 0.71 | LMNA (0.36) | LMNA | |
| SCHEMBL19120784 | 0.70 | MAPT (0.46) | LMNAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017076968-A1 | COMPOUNDS FOR TREATMENT OF HYPOPROLIFERATIVE DISORDERS | LU LICENSE AB (SE) | 2017-05-11 | — | — | WO | disclosed |