Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18849152 | 0.93 | NCF1 (0.40) | HRH4HTR3A | |
| SCHEMBL18639230 | 0.92 | ADRA2C (0.32) | ADRA2CALDH1A1MAPTGAAKMT2A | |
| SCHEMBL18052758 | 0.81 | ALDH1A1 (0.38) | ADRA2CALDH1A1MAPTGAAKMT2A | |
| SCHEMBL20780839 | 0.79 | — | — | |
| SCHEMBL12663101 | 0.79 | CHRNA7 (0.42) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL17934702 | 0.79 | — | — | |
| SCHEMBL13650809 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4EUSP2HTR3AHTR3E | |
| SCHEMBL30425332 | 0.76 | LMNA (0.36) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL19120784 | 0.76 | MAPT (0.46) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL24378189 | 0.75 | HSD17B10 (0.42) | ALDH1A1MAPTGAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298198-A | Novel compounds and compositions for targeted therapy of kidney-related cancers | 上海盟科药业股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-113214287-B | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2023-10-20 | — | — | CN | disclosed |
| CN-116723843-A | Pharmaceutical combination of SOS1 inhibitors for the treatment and/or prevention of cancer | 鲁宾有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-111032643-B | Quinolinone compounds | 詹森药业有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115803330-A | Salts and crystalline forms of 4-amino-5- (6- (4-methylpiperazin-1-yl) -1H-benzo [ d ] imidazol-2-yl) thieno [2,3-b ] pyridin-6 (7H) -one | 大学健康网络 | 2023-03-14 | — | — | CN | disclosed |
| CN-115298198-A | Novel compounds and compositions for targeted therapy of kidney-related cancers | 上海盟科药业股份有限公司 | 2022-11-04 | — | — | CN | disclosed |