Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884168 | 1.00 | CA12 (0.53) | CA12CA1CA9PREPNPC1 | |
| SCHEMBL840971 | 0.83 | CA1 (0.61) | CA12CA1CA9PREPNPC1 | |
| SCHEMBL30043665 | 0.83 | CA1 (0.61) | CA12CA1CA9PREPNPC1 | |
| SCHEMBL12909293 | 0.77 | CA12 (0.55) | CA12CA1CA9PREPNPC1 | |
| SCHEMBL8677800 | 0.77 | MAOA (0.65) | CA12CA1CA9NPC1RAB9A | |
| SCHEMBL29853363 | 0.76 | MAPT (0.63) | CA12CA1CA9NPC1RAB9A | |
| SCHEMBL26781086 | 0.76 | MAPT (0.63) | CA12CA1CA9NPC1RAB9A | |
| SCHEMBL6763899 | 0.74 | PREP (0.53) | CA12CA1CA9PREPKDM4E | |
| SCHEMBL4938350 | 0.74 | CA12 (0.54) | CA12CA1CA9PREPNPC1 | |
| SCHEMBL26768877 | 0.72 | MAPT (0.50) | CA12CA1CA9PREPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935836-B2 | Compounds comprising a linear series of five fused carbon rings, and preparation thereof | FALLIS ALEXANDER GRAHAM | 2011-05-03 | — | — | US | disclosed |
| US-7655809-B2 | Compounds comprising a linear series of five fused carbon rings, and preparation thereof | UNIVERSITY OF OTTAWA (CA) | 2010-02-02 | — | — | US | disclosed |
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | FALLIS ALEXANDER GRAHAM | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | JUP, CDH1, EML4 | CA12 926/4885CA1 1324/4885CA9 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.