Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL18863735

N=C1N[C@H]2[C@H](CS[C@H]2CCCCC(=O)NCCOCCNC(=O)c2cc(NC(=O)NCCOCCOCCN(Cc3ccccc3)C(=O)O)cc(C(=O)NCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=N)N[C@@H]43)c2)N1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 6/20 0.50
▸ NSD2 O96028 1/20 0.44
▸ NSD3 Q9BZ95 1/20 0.44
▸ PKM P14618 2/20 0.42
▸ HSP90AB1 P08238 1/20 0.41
▸ LY6K Q17RY6 1/20 0.40
▸ PRSS1 P07477 2/20 0.40
▸ PRSS2 P07478 2/20 0.40
▸ PRSS3 P35030 2/20 0.40
▸ TPSAB1 Q15661 2/20 0.40
▸ F2 P00734 1/20 0.40
▸ L3MBTL3 Q96JM7 1/20 0.40
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ PLG P00747 1/20 0.40
▸ KDM1A O60341 3/20 0.39
▸ GBA1 P04062 1/20 0.39
▸ BCL9 O00512 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL22828936 0.89 PKM (0.46) FOLH1NSD2NSD3PKMLY6K
Trifluoroacetic Acid SCHEMBL18334640 0.87 PKM (0.45) FOLH1NSD2NSD3PKMLY6K
SCHEMBL17039663 0.85 PKM (0.46) FOLH1NSD2NSD3PKMHSP90AB1
Trifluoroacetic Acid SCHEMBL18863752 0.84 L3MBTL3 (0.43) FOLH1NSD2NSD3PKMLY6K
Trifluoroacetic Acid SCHEMBL31622828 0.83 NSD2 (0.40) FOLH1NSD2NSD3PKMHSP90AB1
SCHEMBL18876552 0.82 PKM (0.49) FOLH1NSD2NSD3PKMHSP90AB1
SCHEMBL17039702 0.82 PKM (0.49) FOLH1NSD2NSD3PKMLY6K
SCHEMBL25923029 0.80 GBA1 (0.52) FOLH1NSD2NSD3PKMHSP90AB1
Trifluoroacetic Acid SCHEMBL23199551 0.80 GBA1 (0.45) FOLH1NSD2NSD3PKMHSP90AB1
SCHEMBL17039703 0.80 L3MBTL3 (0.45) FOLH1NSD2NSD3PKMLY6K

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286285-B2 Modified biotin, streptavidin mutant, and usage of them SAVID THERAPEUTICS INC. (JP) 2022-03-29 — — US disclosed
US-20170145063-A1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM SAVID THERAPEUTICS INC. (JP) 2017-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145063-A1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM BTD, HLCS, BROX FOLH1 1121/4885NSD2 2973/4885NSD3 2856/4885
US-11286285-B2 Modified biotin, streptavidin mutant, and usage of them BTD, HLCS, BROX FOLH1 1121/4885NSD2 2973/4885NSD3 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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