Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845008 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL5103407 | 0.88 | HCAR3 (0.64) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL5983182 | 0.88 | KAT2B (0.69) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL16848719 | 0.88 | MAPT (0.54) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL6536602 | 0.84 | HCAR3 (0.62) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL18075204 | 0.84 | HCAR3 (0.67) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL18075096 | 0.84 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL8053888 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL127370 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL29392416 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | claimed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| US-11053212-B2 | Benzimidazole derivatives as bromodomain inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-07-06 | — | — | US | disclosed |
| CN-107635989-B | Benzimidazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权开发有限公司 | 2020-12-08 | — | — | CN | disclosed |
| US-20200039953-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| US-10442786-B2 | Benzimidazole derivatives as bromodomain inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-10-15 | — | — | US | disclosed |
| EP-3549939-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-09 | — | — | EP | disclosed |
| EP-3271349-B1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-05-15 | — | — | EP | disclosed |
| US-20180044317-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-02-15 | — | — | US | disclosed |
| EP-3271349-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-01-24 | — | — | EP | disclosed |
| EP-1647267-A1 | Cosmetic, dermatological and pharmaceutical compositions | Clariant Produkte (Deutschland) GmbH (DE) | 2006-04-19 | — | — | EP | disclosed |
| US-20050255075-A1 | Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes | CLARIANT GMBH | 2005-11-17 | — | — | US | disclosed |
| US-20050204484-A1 | Hair colorants | CLARIANT GMBH | 2005-09-22 | — | — | US | disclosed |
| EP-1576945-A1 | Cosmetic or pharmaceutic composition comprising modified polyorganosiloxane | Clariant GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| EP-1555012-A1 | Hair dyeing composition containing anthraquinones | Clariant GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | disclosed |
| US-4835314-A | 2-nitroaniline derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442786-B2 | Benzimidazole derivatives as bromodomain inhibitors | BRD4, BRD1, BRPF3 | ALDH1A1 2160/4885TSHR 864/4885TDP1 2392/4885 |
| US-20200039953-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD1, BRPF3 | ALDH1A1 2160/4885TSHR 864/4885TDP1 2392/4885 |
| US-20180044317-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD1, BRPF3 | ALDH1A1 2160/4885TSHR 864/4885TDP1 2392/4885 |
| US-11053212-B2 | Benzimidazole derivatives as bromodomain inhibitors | BRD4, BRD1, BRPF3 | ALDH1A1 2160/4885TSHR 864/4885TDP1 2392/4885 |
| US-20050204484-A1 | Hair colorants | MC1R, CYB5R3, AR | ALDH1A1 925/4885TSHR 1543/4885TDP1 4597/4885 |
| US-20050255075-A1 | Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes | POLH, SGMS2, SGMS1 | ALDH1A1 3087/4885TSHR 2675/4885TDP1 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.