Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 7/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731029 | 0.94 | SCN9A (0.41) | SCN9AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9731176 | 0.91 | HCAR2 (0.38) | HCAR2KMOMMP13 | |
| SCHEMBL9731177 | 0.84 | HDAC1 (0.36) | SCN9AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL6480080 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDKMO | |
| SCHEMBL9731199 | 0.79 | ALDH1A1 (0.40) | KDM4EALDH1A1KMO | |
| SCHEMBL18864232 | 0.78 | FTO (0.53) | SCN9AKDM4EALDH1A1MLYCD | |
| SCHEMBL9731397 | 0.78 | NTRK2 (0.41) | KMOMMP13 | |
| SCHEMBL9732419 | 0.78 | KMO (0.36) | KDM4EALDH1A1KMO | |
| SCHEMBL9730983 | 0.78 | HCAR2 (0.41) | HCAR2KDM4EALDH1A1TSHR | |
| SCHEMBL590269 | 0.77 | OXTR (0.44) | SCN9AKDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3240776-A | — | — | None | — | — | JP | disclosed |
| US-5130317-A | Immunosuppressants and fibrosuppressants for metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| JP-H03240776-A | PYRIMIDINE-4,6-DICARBOXYLIC ACID DIAMIDE | HOECHST AG | 1991-10-28 | — | — | JP | disclosed |