Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993032 | 0.93 | KMT2A (0.49) | ALDH1A1KMT2ACYP3A4MEN1CYP1A2 | |
| SCHEMBL6990109 | 0.86 | LPAR1 (0.53) | ALDH1A1KMT2ACYP3A4MEN1KDM4E | |
| SCHEMBL6986947 | 0.83 | LPAR1 (0.51) | AOC3SMN1; SMN2KDM6BKDM5AKDM4D | |
| SCHEMBL6985928 | 0.82 | KDM5B (0.49) | ALDH1A1L3MBTL1KDM4EMAPTKDM6B | |
| SCHEMBL6239722 | 0.82 | KDM5B (0.49) | ALDH1A1L3MBTL1KDM4EMAPTKDM6B | |
| SCHEMBL6235516 | 0.80 | KDM4C (0.49) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL6990114 | 0.79 | LPAR1 (0.49) | ALDH1A1KMT2ACYP3A4MEN1CA12 | |
| SCHEMBL18864232 | 0.78 | FTO (0.53) | ALDH1A1L3MBTL1KDM4EMAPTKDM6B | |
| SCHEMBL6989313 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1KMT2ACYP3A4CYP2D6LMNA | |
| SCHEMBL6988711 | 0.77 | CA12 (0.51) | ALDH1A1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |