SCHEMBL18864321

SCHEMBL18864321

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nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 8/20 0.47
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.41
LGALS3 P17931 6/20 0.39
LGALS4 P56470 4/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
LGALS9 O00182 1/20 0.35
LGALS1 P09382 1/20 0.35
LGALS7; LGALS7B P47929 1/20 0.35
FGF1 P05230 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6129339 0.86 LGALS8 (0.52) LGALS8ALDH1A1THRBLGALS3LGALS4
SCHEMBL16869486 0.77 DPP4 (0.36)
SCHEMBL10972064 0.76 LGALS3 (0.46) LGALS8LGALS3LGALS4
SCHEMBL17283396 0.76 LGALS8 (0.58) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL701054 0.74 LGALS8 (0.56) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL5024268 0.74 DPP4 (0.40)
SCHEMBL1674815 0.74 LGALS8 (0.56) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL2710870 0.73 MAPK1 (0.41) LGALS8ALDH1A1THRBLGALS3LGALS9
SCHEMBL16327733 0.71 LGALS8 (0.60) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL10781121 0.70 LGALS8 (0.57) LGALS8LGALS3FGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent SENOMYX INC (US) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent TAS2R8, TAS2R45, TAS2R40 LGALS8 580/4885ALDH1A1 263/4885THRB 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.