SCHEMBL18873949

SCHEMBL18873949

O=C1c2cc(Oc3ccccc3)c3c4c(Oc5ccccc5)cc5c6c(cc(Oc7ccccc7)c(c7c(Oc8ccccc8)cc(c2c37)C(=O)N1c1ccccc1)c64)C(=O)N(c1ccccc1)C5=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 1/20 0.44
▸ ESR1 P03372 1/20 0.44
▸ KMT2A Q03164 5/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ MGLL Q99685 1/20 0.42
▸ ALDH1A1 P00352 4/20 0.41
▸ POLB P06746 1/20 0.41
▸ HTT P42858 2/20 0.41
▸ NTRK1 P04629 3/20 0.41
▸ NTRK2 Q16620 3/20 0.41
▸ NTRK3 Q16288 1/20 0.41
▸ HSPA1A P0DMV8 1/20 0.41
▸ PABPC1 P11940 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ BRD4 O60885 1/20 0.40
▸ MAPT P10636 2/20 0.40
▸ IGF1R P08069 2/20 0.40
▸ FGFR1 P11362 2/20 0.40
▸ HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021803 0.90 KMT2A (0.56) GRM5KMT2AMEN1ALDH1A1HTT
SCHEMBL10021805 0.84 MEN1 (0.37) GRM5KMT2AMEN1ALDH1A1POLB
SCHEMBL24011822 0.81 GSTP1 (0.40) GRM5KMT2AALDH1A1BRD4HPGD
SCHEMBL25014573 0.81 NR1H2 (0.35) GRM5KMT2AMEN1MGLLALDH1A1
SCHEMBL13498707 0.81 DPP4 (0.46) KMT2AMEN1ALDH1A1POLBNTRK1
SCHEMBL24011924 0.80 GSTP1 (0.39) GRM5MGLLNTRK1NTRK2NTRK3
SCHEMBL18289876 0.80 ALDH1A1 (0.37) KMT2AMEN1MGLLALDH1A1HTT
SCHEMBL24011859 0.78 MEN1 (0.47) KMT2AMEN1ALDH1A1POLBHTT
SCHEMBL902459 0.78 ANPEP (0.49) NTRK1NTRK2NTRK3BRD4MAPT
SCHEMBL29357723 0.78 ANPEP (0.49) NTRK1NTRK2NTRK3BRD4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370967-B2 Light emitting apparatus and electronic device comprising light emitting apparatus DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-28 — — US disclosed
EP-3465332-B1 LIGHT EMITTING APPARATUS AND ELECTRONIC DEVICE COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-07-21 — — EP disclosed
US-20200317999-A1 LIGHT EMITTING APPARATUS AND ELECTRONIC DEVICE COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-08 — — US disclosed
US-20190241801-A1 LIGHT EMITTING APPARATUS AND ELECTRONIC DEVICE COMPRISING LIGHT EMITTING APPARATUS DOW CHEMICAL (CHINA) INVESTMENT COMPANY LIMITED (CN) 2019-08-08 — — US disclosed
US-20190071599-A1 LIGHT EMITTING NANOPARTICLES AND PROCESS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-03-07 — — US disclosed
WO-2018068299-A1 LIGHT EMITTING APPARATUS AND ELECTRONIC DEVICE COMPRISING LIGHT EMITTING APPARATUS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-19 — — WO disclosed
WO-2017079911-A1 LIGHT EMITTING NANOPARTICLES AND PROCESS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317999-A1 LIGHT EMITTING APPARATUS AND ELECTRONIC DEVICE COMPRISING THE SAME CRY1, CRY2, LAGE3 GRM5 1761/4885ESR1 13/4885KMT2A 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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