Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10533927 | 0.98 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1POLBTDP1MAPT | |
| SCHEMBL12017388 | 0.81 | APP (0.50) | L3MBTL1ALDH1A1POLBTDP1MAPT | |
| SCHEMBL22593391 | 0.81 | MRGPRX1 (0.43) | L3MBTL1ALDH1A1POLBMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL28062296 | 0.80 | APP (0.49) | L3MBTL1ALDH1A1POLBTDP1MAPT | |
| SCHEMBL28288419 | 0.80 | MAPT (0.52) | L3MBTL1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1400354 | 0.79 | MEN1 (0.49) | L3MBTL1ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL7723877 | 0.76 | MRGPRX1 (0.40) | L3MBTL1ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL7733793 | 0.76 | KDM4E (0.43) | L3MBTL1POLBTDP1MAPTKDM4E | |
| SCHEMBL24018796 | 0.75 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL22729471 | 0.75 | MRGPRX1 (0.40) | L3MBTL1ALDH1A1POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025917-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-20240025917-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-20220289679-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-4005637-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2022-06-01 | — | — | EP | disclosed |
| WO-2022109161-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2022-05-27 | — | — | WO | disclosed |
| US-20200283398-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2020-09-10 | — | — | US | disclosed |
| US-10442777-B2 | Use of substituted oxadiazoles for combating phytopathogenic fungi | BASF SE (DE) | 2019-10-15 | — | — | US | disclosed |
| US-20190016694-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2019-01-17 | — | — | US | disclosed |
| US-20170144980-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016694-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | CYP51A1, DPM1, NOX1 | L3MBTL1 3470/4885ALDH1A1 1574/4885POLB 2670/4885 |
| US-20240025917-A1 | PLASMA KALLIKREIN INHIBITORS | KLKB1, SERPINE1, KLK5 | L3MBTL1 4403/4885ALDH1A1 1701/4885POLB 4522/4885 |
| US-10442777-B2 | Use of substituted oxadiazoles for combating phytopathogenic fungi | CYP51A1, DPM1, NOX1 | L3MBTL1 3470/4885ALDH1A1 1574/4885POLB 2670/4885 |
| US-20220289679-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | L3MBTL1 1929/4885ALDH1A1 1563/4885POLB 3724/4885 |
| US-20200283398-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | CYP51A1, DPM1, NOX1 | L3MBTL1 3470/4885ALDH1A1 1574/4885POLB 2670/4885 |
| US-20170144980-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | CYP51A1, DPM1, NOX1 | L3MBTL1 3470/4885ALDH1A1 1574/4885POLB 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.