Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733793 | 0.84 | KDM4E (0.43) | MRGPRX1CHRM2MEN1MAPTKMT2A | |
| SCHEMBL7736582 | 0.80 | GAA (0.43) | CHRM2MAPTGAAHTTRXFP1 | |
| SCHEMBL22729471 | 0.76 | MRGPRX1 (0.40) | MRGPRX1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL18884397 | 0.76 | L3MBTL1 (0.48) | MRGPRX1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL22593391 | 0.76 | MRGPRX1 (0.43) | MRGPRX1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12017388 | 0.76 | APP (0.50) | MRGPRX1ALDH1A1MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL10533927 | 0.75 | L3MBTL1 (0.52) | MRGPRX1ALDH1A1MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28062296 | 0.75 | APP (0.49) | MRGPRX1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28288419 | 0.74 | MAPT (0.52) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7733773 | 0.74 | CHRM2 (0.62) | CHRM2ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |