Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017388 | 0.78 | APP (0.50) | MRGPRX1L3MBTL1KDM4EPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL28062296 | 0.77 | APP (0.49) | MRGPRX1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL22729539 | 0.76 | CHRM2 (0.53) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7723877 | 0.76 | MRGPRX1 (0.40) | MRGPRX1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL7733793 | 0.76 | KDM4E (0.43) | MRGPRX1L3MBTL1KDM4EPOLBMEN1 | |
| SCHEMBL23144402 | 0.76 | LRRK2 (0.44) | MRGPRX1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22593391 | 0.75 | MRGPRX1 (0.43) | MRGPRX1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL18884397 | 0.75 | L3MBTL1 (0.48) | MRGPRX1L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL30871188 | 0.74 | ALDH1A1 (0.48) | MRGPRX1KDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10533927 | 0.73 | L3MBTL1 (0.52) | MRGPRX1L3MBTL1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | MRGPRX1 1077/4885L3MBTL1 1536/4885KDM4E 1315/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | MRGPRX1 1128/4885L3MBTL1 1525/4885KDM4E 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.