SCHEMBL1888751

SCHEMBL1888751

CCCc1cc(CC)c(-c2c(-c3c(CC)cc(CCC)cc3CC)c(-c3c(CC)cc(CCC)cc3CC)c3c(c2-c2c(CC)cc(CCC)cc2CC)=c2ccccc2=3)c(CC)c1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.33
BACE1 P56817 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
GPR84 Q9NQS5 2/20 0.31
TP53 P04637 1/20 0.30
P2RY4 P51582 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1887999 0.77 GPR84 (0.31) GPR84
SCHEMBL1884685 0.75 KDM4E (0.36) ATMGPR84
SCHEMBL9723265 0.69 ALDH1A1 (0.47) TP53P2RY4
SCHEMBL11055022 0.68 ATM (0.47) ATMGPR84
SCHEMBL28136231 0.67 MAPT (0.39) CNR1CNR2TP53
SCHEMBL1885153 0.66 HSPA5 (0.41) TP53
SCHEMBL1023550 0.65 DHFR (0.47) BACE1CNR1CNR2
SCHEMBL11497456 0.65 HTT (0.47) BACE1CNR1CNR2CA2
SCHEMBL9734907 0.65 CNR1 (0.48) BACE1CNR1CNR2GPR84CA2
SCHEMBL11028811 0.65 TP53 (0.52) ATMCNR2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed