Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180423 | 0.78 | GPR3 (0.44) | NPC1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL18554727 | 0.76 | GABRA1 (0.47) | TP53 | |
| SCHEMBL30500513 | 0.74 | NPC1 (0.53) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL674014 | 0.71 | NPC1 (0.35) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL26036292 | 0.71 | LMNA (0.44) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL28860095 | 0.70 | MAPT (0.58) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL29154385 | 0.70 | ALDH1A1 (0.53) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL1888751 | 0.69 | ATM (0.33) | P2RY4TP53 | |
| SCHEMBL1886830 | 0.69 | MEN1 (0.31) | GAA | |
| SCHEMBL1888188 | 0.69 | MEN1 (0.31) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162406-A | Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol | THE DOW CHEMICAL COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0036278-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION OF IMPROVED HEAT STABILITY AND SHAPED ARTICLES THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4427814-A | DIPHOSPHONITE STABILIZER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-01-24 | — | — | US | disclosed |
| EP-0036278-A1 | Polyphenylene ether resin composition of improved heat stability and shaped articles thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-09-23 | — | — | EP | disclosed |