Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.70 |
| ▸ | FPGS | Q05932 | 2/20 | 0.70 |
| ▸ | GART | P22102 | 5/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 4/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homocysteine SCHEMBL27706413 | 1.00 | SOST (0.70) | SOSTFPGSGARTDHFRMTHFD1 | |
| Glutamic Acid SCHEMBL4628258 | 0.93 | SOST (0.80) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL3953439 | 0.93 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL50298 | 0.93 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL15121249 | 0.93 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL716106 | 0.93 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL28469783 | 0.92 | SOST (0.77) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL27708884 | 0.92 | SOST (0.77) | SOSTFPGSGARTDHFRMTHFD1 | |
| Tetrahydrofolate SCHEMBL27727181 | 0.90 | SOST (0.87) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL28206357 | 0.89 | SOST (0.79) | SOSTFPGSGARTDHFRMTHFD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140142060-A1 | METHOD AND DEVICE FOR IDENTIFICATION OF ONE CARBON PATHWAY GENE VARIANTS AS STROKE RISK MARKERS, COMBINED DATA MINING, LOGISTIC REGRESSION, AND PATHWAY ANALYSIS | Hyde Park West, LLC (US) | 2014-05-22 | — | — | US | disclosed |
| US-8170852-B2 | Data structures and methods for modeling Saccharomyces cerevisiae metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-01 | — | — | US | disclosed |
| US-8046198-B2 | Methods for determining susceptibility to developmental disorders due to a combination of genetic and environmental factors | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110212460-A1 | ASSAY FOR NITROUS OXIDE NEUROLOGIC SYNDROME | HOGAN KIRK J | 2011-09-01 | — | — | US | disclosed |
| US-7939115-B2 | Fruits (pomegranate and citrus bioflavonoids), vegetables (asparagus, lutein, lycopene), herbs, vitamins, and minerals; chromatin expression; for correcting dietary deficiency of phytochemicals, improving plasma concentrations of antioxidant nutrients, and increasing activity of genetic/DNA repair | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2011-05-10 | — | — | US | disclosed |
| US-20100280803-A1 | Compositions and Methods for Modeling Saccharomyces cerevisiae Metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-11-04 | — | — | US | disclosed |
| US-20080226744-A1 | DIETARY SUPPLEMENT AND RELATED METHOD | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2008-09-18 | — | — | US | disclosed |
| WO-2008060845-A2 | RADIOLABELED VITAMIN B12 AND ITS DERIVATIVES USEFUL FOR POSITRON EMISSION TOMOGRAPHY IMAGING | NAVISCAN PET SYSTEMS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| US-20060160104-A1 | Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2006-07-20 | — | — | US | disclosed |
| US-6912492-B1 | Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 2005-06-28 | — | — | US | disclosed |
| EP-1171162-A2 | COBALAMIN CONJUGATES USEFUL AS ANTITUMOR AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6210950-B1 | NNUCLEOTIDE SEQUENCES WHICH CODE HUMAN DIHYDROFOLATE REDUCTASE; FOR DIAGNOSING, PREVENTING AND TREATING DEVELOPMENTAL DISORDERS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2001-04-03 | — | — | US | disclosed |
| WO-2000062808-A2 | COBALAMIN CONJUGATES USEFUL AS ANTITUMOR AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2000-10-26 | — | — | WO | disclosed |
| WO-1998059242-A1 | HOMOCYSTEINE ASSAY | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| EP-0883627-A1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997018231-A1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0191133-A2 | Stable salts of SAM with polyanions | GIBIPHARMA S.p.A. (IT) | 1986-08-20 | — | — | EP | disclosed |