Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL2836497 | 0.97 | SPHK1 (0.50) | TSHRSPHK1THRBLMNACYP2D6 | |
| Hexane SCHEMBL7047481 | 0.88 | GPR84 (0.43) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| Hexane SCHEMBL1730411 | 0.87 | TSHR (0.50) | TSHRSPHK1THRBSMN1; SMN2LMNA | |
| Butyl Alcohol SCHEMBL28328341 | 0.87 | ALDH1A1 (0.55) | TSHRSPHK1SMN1; SMN2LMNACYP2D6 | |
| Heptane SCHEMBL7200232 | 0.86 | SPHK1 (0.42) | TSHRSPHK1MAPTGPR84FFAR1 | |
| Hexane SCHEMBL29171036 | 0.86 | HSD17B10 (0.46) | TSHRSPHK1THRBCYP1A2CYP3A4 | |
| Hexane SCHEMBL23782662 | 0.84 | TSHR (0.47) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Hexane SCHEMBL7784664 | 0.84 | TSHR (0.47) | TSHRSPHK1THRBSMN1; SMN2LMNA | |
| Hexane SCHEMBL22689637 | 0.84 | TSHR (0.47) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Hexane SCHEMBL8457635 | 0.84 | TSHR (0.47) | TSHRSPHK1THRBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114480360-B | Method for preparing diglyceride by immobilized Sn-2 lipase | 山东省农业科学院 | 2024-03-12 | — | — | CN | disclosed |
| US-20230183758-A1 | METHOD FOR PREPARING DIACYLGLYCEROL BY IMMOBILIZED SN-2 LIPASE | SHANDONG ACAD AGRICULTURAL SCIENCES (CN) | 2023-06-15 | — | — | US | disclosed |
| CN-114480360-A | Method for preparing diglyceride by immobilized Sn-2 lipase | 山东省农业科学院 | 2022-05-13 | — | — | CN | disclosed |
| CN-106442793-B | A kind of detection method of the intermediate for preparing Afatinib and its enantiomter | 河北神威药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-106442793-A | Method for preparing and detecting intermediate and corresponding isomer of afatinib | 河北神威药业有限公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2819956-A1 | METHODS AND KITS FOR DETECTION OF COENZYME Q10 | Berg LLC (US) | 2015-01-07 | — | — | EP | disclosed |
| WO-2013131068-A9 | METHODS AND KITS FOR DETECTION OF COENZYME Q10 | BERG PHARMA, LLC (US) | 2013-10-24 | — | — | WO | disclosed |
| WO-2013131068-A1 | METHODS AND KITS FOR DETECTION OF COENZYME Q10 | BERG PHARMA, LLC (US) | 2013-09-06 | — | — | WO | disclosed |
| US-7935829-B2 | Manufacture of thiolactones | DSM IP ASSETS B.V. (NL) | 2011-05-03 | — | — | US | disclosed |
| US-20090048455-A1 | Manufacture of Thiolactones | DSM IP ASSETS B.V. (NL) | 2009-02-19 | — | — | US | disclosed |
| US-4919803-A | NAPROXEN COVALENTLY BONDED TO AMINOPROPYL SILANIZED SILICA PACKING MATERIAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1990-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048455-A1 | Manufacture of Thiolactones | TST, TMT1A, TXN | TSHR 834/4885SPHK1 3198/4885THRB 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.